From preservatives to flavor enhancers, there are many ingredients in our food that we don’t necessarily know about if we don’t read labels carefully. One of these ingredients is propylene glycol. Found in a variety of foods, including baked goods, ice cream, and salad dressing, propylene glycol is a food additive that has been deemed safe by the Food and Drug Administration (FDA) (9). While propylene glycol is considered safe, there are some concerns about its potential health effects. This article will take a closer look at propylene glycol in food, what it is, and what research says about its safety.
If you’ve noticed that the cake you baked from a store-bought mix had an extra moist texture, it’s probably because the mix contained a form of propylene glycol. This ingredient is also added to salad dressings to help keep the spices evenly dispersed and to prevent oil separation.
Propylene glycol is a compound that belongs to a group of chemicals known as alcohols. It’s a clear, colorless, and odorless liquid that is water-soluble and has a sweet taste (1).
Propylene glycol is used as a food additive because it can help keep food moist, prevent spoilage, and enhance flavor. It’s also used in cosmetics and pharmaceuticals (15).
Many are alarmed by this ingredient because it’s confused with ethylene glycol, which is found in antifreeze and is considered poisonous (6). However, propylene glycol is much less toxic than ethylene glycol and is used in a variety of products, including food.
Other names for propylene glycol are 1,2-propanediol, 1,2-dihydroxy propane, Methyl ethyl glycol, and Trimethyl glycol (15).
On ingredient lists, it may be listed under Propylene glycol, Propylene glycol mono and diester, E1520 or 1520.
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In food applications, propylene glycol is often used as (16) (19):
Propylene glycol is also used in:
Many foods contain this ingredient. While the propylene glycol food list below isn’t comprehensive, it contains most of the common foods that contain this ingredient.
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The FDA has categorized propylene glycol as “generally recognized as safe” (GRAS), which means that it’s safe for use in food (9). The European Union (EU) has also approved propylene glycol as a food additive (2).
While propylene glycol is considered safe, there are some concerns about its potential effects on health. These concerns stem from the fact that propylene glycol is metabolized into lactic acid, which is naturally produced in the body but can be harmful in high concentrations.
In one study, rats that were fed a diet containing very high amounts of propylene glycol for six weeks had increased levels of lactic acid in their blood, but it was not enough to cause harm (metabolic acidosis) (11).
Propylene glycol is also a skin irritant, and it’s possible that it could be harmful if inhaled (7). Inhaling large amounts of propylene glycol has been linked to lung damage in animals (8).
So, while propylene glycol is considered safe when used in food, there are some potential risks to be aware of. If you’re concerned about the safety of this ingredient, you may want to avoid foods that contain it.
There is a lot of conflicting information about the dangers of propylene glycol. Some people claim that it is perfectly safe, while others say that it can cause a variety of health problems.
Research shows that propylene glycol has very low toxicity (10). Poisoning rarely occurs from propylene glycol unless very large amounts are ingested, more often through medication than food.
Potential effects of ingesting very large amounts of propylene glycol include:
The kidney and liver work together to remove propylene glycol from the body. However, people with kidney or liver diseases may not be able to process propylene glycol as well, which can lead to a buildup of the chemical in their bodies. This can be dangerous and potentially lead to serious health problems (2) (18).
Both infants and pregnant women have low levels of the enzyme needed to break down propylene glycol. This means that they may be more likely to experience side effects from exposure to the chemical (13) (16).
Seizures are a potential side effect in young children, while pregnant women may experience reproductive toxicity (14).
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People with allergies to propylene glycol may experience a variety of symptoms when they are exposed to this chemical (4). These can range from mild (such as skin irritation) to severe (such as difficulty breathing). In rare cases, anaphylactic shock may occur.
Very high doses of propylene glycol have been shown to cause heart attacks in animals. It rapidly decreases heart rate, causes low blood pressure, and can lead to cardiac arrest (3).
However, it’s important to note that these effects have only been seen in animals at very high doses. There is no evidence that propylene glycol poses a risk of heart attack in humans.
There is one reported case of a child suffering the loss of heart function while being treated for burns with a propylene glycol-based ointment (12).
The child received a very high dose of propylene glycol (the ointment was applied over a large area of the child’s body), and it is not clear if the propylene glycol or other factors contributed to the heart problems (12).
Large doses of propylene glycol can cause neurological effects, such as slurred speech, dizziness, and drowsiness (5).
Scientists observed that these symptoms disappear within 6 hours (17). It’s important to note that these symptoms were observed due to the ingredient in the medication, not food.
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While propylene glycol is present in many food items, there are some ways to avoid it if you’re concerned about your exposure.
While propylene glycol is considered safe for most people, some groups may be more susceptible to the potential side effects of the chemical. If you fall into one of these groups, it is important to be aware of the risks and take steps to avoid excessive exposure to propylene glycol.
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